Search results for "Surface Immunoglobulin"

showing 2 items of 2 documents

T cells can present antigens such as HIV gp120 targeted to their own surface molecules

1988

To trigger class II-restricted T cells, antigen presenting cells have to capture antigens, process them and display their fragments in association with class II molecules. In most species, activated T cells express class II molecules; however, no evidence has been found that these cells can present soluble antigens. This failure may be due to the inefficient capture, processing or display of antigens in a stimulatory form by T-cells. The capture of a soluble antigen, which is achieved by nonspecific mechanisms in macrophages and dendritic cells, can be up to 10(3) times more efficient in the presence of surface receptors, such as surface immunoglobulin on B cells that specifically bind anti…

Antigens Differentiation T-LymphocyteHerpesvirus 4 HumanImmunoprecipitationSurface ImmunoglobulinT-LymphocytesAntigen presentationRetroviridae ProteinsAntigen-Presenting CellsHIV Envelope Protein gp120Viral Envelope ProteinsAntigenHistocompatibility AntigensHumansAntigen-presenting cellAntigens ViralCell Line TransformedB-LymphocytesMultidisciplinarybiologyAntibodies MonoclonalHIVMolecular biologyCell culturebiology.proteinAntibodyCD8Nature
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K Cell Activity of Normal and Chronic Lymphocytic Leukaemia Lymphocytes: Association with Lymphocytes bearing Receptors for Human C3b

1977

Surface properties of effector cells in antibody-dependent cell mediated cytotoxicity (ADCC) are at present under intensive investigation. Among these cells a lymphocyte population (K cells) has been described with receptors for the Fc portion of IgG (4), receptors for complement (11) and lacking receptors for sheep red blood cells (SRBC) and surface immunoglobulin (13). The purpose of the present study was to investigate more thoroughly the relationship between K cell activity in ADCC and cells bearing receptors for C3b and C3d.

Antibody-dependent cell-mediated cytotoxicityeducation.field_of_studyLymphocytic leukaemiaSurface ImmunoglobulinEffectorChemistryLymphocytePopulationchemical and pharmacologic phenomenak-cellMolecular biologymedicine.anatomical_structuremedicineReceptoreducation
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